Introduction It has long been recognized that a very low number of patients are referred into clinical trials. According to estimates, only 2–3% of patients are referred for trials, a low number. Poor accrual is a threat to the timely completion of increasingly large studies, which are very important considering the criticalness of properly evaluating the latest treatments, while also avoiding the potential for random error associated with small studies. Referral for a clinical trial is not simple as it can be quite difficult with numerous steps to be taken in order to become a part of the process, such as: • Patients need to be identified • The study concept must be introduced • The positive and negatives of experimental therapy must all be outlined • The risks and benefits of standard treatment als...